Table 4.

Examples of clinical characteristics of LT recipients with different RRI and corresponding 5-year post-LT ESRD cumulative incidence

RRI, Decile, ComponentsPatient 1Patient 2Patient 3Patient 4
RRIa1.0 (reference)1.263.1013.75
 RRI decileThirdFifthEighthTenth
Age (yr)53535353
African AmericanNoNoNoNo
Cholestatic diseaseNoNoNoNo
Hepatitis CNoNoNoNo
DiabetesNoNoYesYes
BMI30303030
Serum creatinine (mg/dl)1.01.21.41.4
Serum bilirubin (mg/dl)3.53.53.53.5
Serum albumin (g/dl)2.92.92.92.9
Serum sodium (mMol/L)140140140140
Status-1NoNoNoNo
Previous LTNoNoNoNo
History of TIPSSNoNoNoNo
On acute dialysis pre-LTNoNoNoYes
5-yr post-LT ESRD cumulative incidence for decile2.3%3.2%6.8%18.0%
  • a RRI=exp[(0.00688×(recipient age−53))+(0.4292 if African American)+(−0.3724 if cholestatic)+(0.2711 if HCV)+(0.7111 if diabetic)+(0.2450 if BMI≥35)+(1.2521×ln(creatinine) if not on dialysis)+(−0.1525×ln(bilirubin/3.5))+(−0.3851×ln(albumin/2.9))+(−0.3706 if sodium<134)+(−0.2671 if status-1)+(0.4359 if previous liver transplant)+(0.3129 if TIPSS)+(1.9097 if on dialysis)].