Table 1.

Descriptive statistics of baseline characteristics stratified by treatment

CharacteristicPlacebo Group
(n=165)α-Tocopherol +ALA Group
(n=160)Total
(n=325)P Valuea
Age (yr)b59 (50, 68) (58±13)59 (50, 65) (58±12)59 (50, 67) (58±12)0.74
Maintenance hemodialysis vintage duration (mo)b31 (19, 61) (53±61)34 (19, 61) (50±51)33 (19, 61) (51±56)0.78
Women42 (69)46 (74)44 (143)0.42
Men58 (96)54 (86)56 (182)
Race
 White42 (69)37 (59)39 (128)0.085
 African American55 (90)61 (98)58 (188)
 Asian0 (0)1 (2)1 (2)
 Other4 (6)1 (1)2 (7)
Ethnicity
 Hispanic
  No93 (154)94 (151)94 (305)0.7
  Yes7 (11)6 (9)6 (20)
Type of vascular access
 Graft27 (45)32 (51)30 (96)0.46
 Fistula67 (110)64 (102)65 (212)
 Catheter with graft0 (0)0 (0)0 (0)
 Catheter with fistula0 (0)1 (1)0 (1)
 Catheter only6 (10)4 (6)5 (16)
Cause of ESRD
 Diabetes38 (63)42 (67)40 (130)0.65
 Hypertension40 (66)39 (62)39 (128)
 GN5 (8)5 (8)5 (16)
 Polycystic kidney disease5 (8)3 (5)4 (13)
 Interstitial nephritis0 (0)1 (2)1 (2)
 Hereditary nephritis0 (0)0 (0)0 (0)
 Other12 (20)10 (16)11 (36)
Diabetes at baseline
 No45 (75)45 (72)45 (147)0.93
 Yes55 (90)55 (88)55 (178)
History of atherosclerotic cardiovascular disease
 No53 (88)46 (73)50 (161)0.16
 Yes47 (77)54 (87)50 (164)
  • Unless otherwise noted, values are the number (percentage) of patients.

  • a Values are expressed as median (interquartile range) and (mean±SD).

  • b P values were obtained from nonparametric Mann–Whitney U tests for continuous variables and chi-squared test for categorical variables.