Table 1.

Solute concentrations in hemodialysis patients and normal subjects

SolutePretreatment Hemodialysis PatientsNormal SubjectsHemodialysis/Normal
Total (mg/dl)Free (mg/dl)Free (%)Total (mg/dl)Free (mg/dl)Free (%)TotalFree
UreaN65±25a13±45
Creatinine10.8±3.3a0.84±0.1813
Phenylacetylglutamine5.2±2.5a4.7±2.5a88±120.05±0.020.04±0.0279±14112122
Hippurate5.3±3.0a3.0±1.8a54±10a0.09±0.070.03±0.0231±759108
Indoxyl Sulfate2.9±1.1a0.27±0.19a8.3±3.4a0.10±0.040.002±0.0022.2±0.730116
p-Cresol Sulfate3.7±1.6a0.26±0.15a6.9±2.5a0.29±0.180.006±0.0032.0±0.51341
  • Values are mean±SD for 25 hemodialysis patients and 16 subjects with normal renal function. Demographic data and the patients' treatment prescriptions are summarized in Supplemental Table 1.

  • a P<0.05 for hemodialysis versus normal value.