Table 3.

F2 isoprostane and F2 isofuran concentrations at baseline and 6 months stratified by treatment

VariablePatients (n)Placebo Group
(n=128)α-Tocopherol +ALA Group
(n=125)P 
Valuea
Median (IQR)Mean±SDMedian (IQR)Mean±SD
Baseline
 F2 isoprostane (ng/ml)2470.060 (0.048, 0.088)0.072±0.0360.063 (0.045, 0.088)0.074±0.0440.98
 F2 isofuran (ng/ml)2520.44 (0.25, 0.84)0.89±1.910.39 (0.24, 0.67)0.69±1.310.23
6 mo
 F2 isoprostane (ng/ml)2490.058 (0.045, 0.081)0.072±0.0540.058 (0.042, 0.086)0.074±0.0590.93
 F2 isofuran (ng/ml)2520.45 (0.26, 0.77)0.79±1.360.38 (0.20, 0.70)0.65±0.900.33
  • IQR, interquartile range.

  • a P values were obtained from nonparametric Mann–Whitney U tests.