Table 3.

Unadjusted odds ratios for the association of APOL1 risk alleles with CKD phenotypes

VariableAdditiveRecessiveDominant
1 versus 0 Risk Alleles2 versus 0 Risk Alleles2 versus 0 or 1 Risk Alleles1 or 2 versus 0 Risk Alleles
OR (95% CI)P ValueOR (95% CI)P ValueOR (95% CI)P ValueOR (95% CI)P Value
eGFR<60 cohort2.80 (1.13 to 6.95)0.036.18 (1.55 to 24.59)0.012.80 (0.89 to 8.82)0.083.05 (1.25 to 7.47)0.01
Nephrotic proteinuria cohort1.89 (0.75 to 4.78)0.180.68 (0.17 to 2.63)0.570.52 (0.14 to 1.95)0.331.40 (0.62 to 3.16)0.42
  • OR, odds ratio; 95% CI, 95% confidence interval.