Table 4.

ESA use, unadjusted and adjusted for hemoglobin concentration, at each time point between two treatments

Time PointPlacebo Groupα-Tocopherol+ALA GroupP Valuea
Patients (n)ESA UsePatients (n)ESA Use
Unadjusted
 Enrollment16536,00016033,6000.54
 Baseline16436,00015932,4000.37
 1 mo15437,20013732,4000.62
 2 mo14736,00012631,2000.58
 3 mo13736,00011836,0000.48
 4 mo13036,00011636,0000.83
 5 mo12536,00011440,8000.82
 6 mo12440,80011442,0000.62
Adjusted for hemoglobin
 Enrollment165321415928570.48
 Baseline163207015926560.34
 1 mo154323913728240.72
 2 mo147318612428800.75
 3 mo136314411734290.50
 4 mo129315811430810.86
 5 mo124333211335790.74
 6 mo123349511435780.71
  • a P value was obtained from nonparametric Mann–Whitney U tests. ESA dose in units.