Table 4.

Agreement of change in eGFR versus change in measured GFR evaluated using 1260 time intervals among 977 participants

Estimate of Change in GFRChange in iGFR (ml/min/1.73 m2)
<−15 (N=297)−15 to +15 (N=800)>15 (N=160)Weighted κDiagonal Agreement (%)
Change in creatinine clearance (ml/min/1.73m2)0.0843.3
 <−15106 (8.4%)211 (16.8%)34 (2.7%)
 −15 to +15143 (11.4)392 (31.2%)79 (6.3%)
 >1548 (3.8%)197 (15.7%)47 (3.7%)
Change in eGFRCr (ml/min/1.73m2)0.0357.8
 <−1546 (3.7%)104 (8.3%)20 (1.6%)
 −15 to +15241 (19.1%)671 (53.3%)131 (10.4%)
 >1510 (0.8%)26 (2.1%)10 (0.8%)
Change in eGFRCys (ml/min/1.73m2)0.0657.3
 <−1554 (4.3%)106 (8.4%)13 (1.0%)
 −15 to +15220 (17.5%)653 (51.9%)134 (10.6%)
 >1523 (1.8%)42 (3.3%)14 (1.1%)
Change in eGFRCr+Cys (ml/min/1.73m2)0.0458.9
 <−1547 (3.7%)87 (6.9%)10 (0.8%)
 −15 to +15240 (19.1%)687 (54.6%)144 (11.4%)
 >1510 (0.8%)27 (2.1%)7 (0.6%)
  • Cell contents are N (%), except for weighted κ-statistics and diagonal agreement proportions.