Table 3.

Association of predialysis systolic BPV and outcomes among 11,291 incident hemodialysis patients

OutcomesEventsCrudeaMinimally AdjustedbFully Adjustedc
HR (95% CI)P ValueHRP ValueHRP Value
All-cause mortality32001.34 (1.30 to 1.39)<0.0011.41 (1.36 to 1.46)<0.0011.17 (1.13 to 1.21)<0.001
CV mortality15981.32 (1.26 to 1.38)<0.0011.38 (1.32 to 1.45)<0.0011.18 (1.12 to 1.23)<0.001
CV events45281.19 (1.15 to 1.23)<0.0011.21 (1.17 to 1.25)<0.0011.10 (1.07 to 1.14)<0.001
  • a Unadjusted model.

  • b Adjusted for age, sex, race, and ethnicity.

  • c Adjusted for demographic characteristics (age, sex, race, and ethnicity), clinical factors (history of diabetes, CVD, CHF, comorbidity index, and BMI), ESRD-related factors (cause of ESRD, Kt/V, and relative fluid removal), laboratory measurements (serum albumin, calcium–phosphate product, hemoglobin, and ferritin), and antihypertensive medications.