Table 1.

Baseline characteristics of 11,291 incident hemodialysis patients by tertiles of predialysis systolic BPV

CharacteristicsOverallTertiles of BPVP Valuea
Lowest (<0.0990)Middle (0.0990–0.1249)Highest (>0.1249)
N (%)11,2913728 (33.0)3841 (34.0)3722 (33.0)
Demographics
 Age (yr)61.9±14.961.7±15.462.7±14.861.5±14.50.85
 Sex (% men)54.862.454.847.2<0.001
 Race (%)
  White58.465.459.550.3
  Black37.330.436.445.2
  Other4.24.24.14.5<0.001
 Ethnicity, Hispanic (%)5.76.25.65.30.27
 Race and ethnicity (%)<0.001
  Black Hispanic0.20.10.30.2
  Black non-Hispanic37.130.336.144.9
  Other4.24.24.14.5
  White Hispanic5.15.84.94.6
  White non-Hispanic53.359.654.645.7
Clinical
 Diabetes (%)64.959.864.470.5<0.001
 CVD (%)55.951.55759.3<0.001
 CHF (%)46.242.946.848.7<0.001
 Comorbidity index (%)
  0–341.446.240.737.2
  4–626.324.426.827.6
  7–919.517.919.421.2
  ≥1012.811.51313.9<0.001
 BMI (kg/m2)27.8±7.027.1±6.027.9±7.028.2±7.8<0.001
 Baseline systolic BP (mmHg)150.0±20.0148.4±19.6149.7±19.9151.9±20.4<0.001
 Baseline systolic BPV
  Mean (SD)0.115±0.0300.084±0.0110.111±0.0070.149±0.022<0.001
  Median (25th, 75th percentiles)0.111 (0.093, 0.133)0.086 (0.077, 0.093)0.111 (0.105, 0.118)0.143 (0.133, 0.159)
 Heart rate (per min)
  Mean (SD)78.1 (11.9)78.3 (11.8)77.9 (11.9)78.2 (12.1)0.06
  Median (25th, 75th percentiles)77.2 (69.5, 85.9)77.5 (69.9, 86)77.1 (69.2, 85.8)77.1 (69.6, 86)
ESRD related
 Cause of ESRD (%)<0.001
  Diabetes49.745.44954.8
  Hypertension28.126.629.128.7
  GN911.396.8
  Other13.116.7139.7
 Average Kt/V1.5±0.31.5±0.31.5±0.31.5±0.30.06
 Relative fluid removal per session (%)3.3±1.33.4±1.43.3±1.33.3±1.40.20
 Achieved target dry weight (%)5154.351.846.9<0.001
Laboratory parameters
 Serum albumin (g/dl)3.66±0.433.7±0.43.7±0.43.6±0.5<0.001
 Calcium phosphate product50.09±15.0550.2±14.550.0±15.050.0±15.70.90
 Hemoglobin (g/dl)12.00±1.2512.1±1.212.0±1.311.9±1.3<0.001
 Ferritin (ng/ml)448.8±335.3443.2±339.0443.6±330.8459.9±336.10.04
Antihypertensive medications (%)<0.001
 Any β-blocker regimen (without RAS)34.135.535.830.8
 Any RAS regimen (without β-blocker)1716.217.217.7
β-Blocker + RAS combination34.830.833.440.2
 Other medications and combinations14.117.513.611.3
Number of antihypertensive medications (%)<0.001
 0–251.957.552.346.1
 3–440.336.640.344.1
 ≥57.767.49.8
  • Data are presented as mean (SD) or column percent unless otherwise specified. Conversion factors: albumin in grams per deciliter to grams per liter, ×10; hemoglobin in grams per deciliter to grams per liter, ×10. No conversion is necessary for ferritin in nanograms per milliliter and micrograms per liter.

  • a P values for continuous variables are P trend obtained from linear regression, and P values for categorical variables are obtained from chi-squared test.