Table 1.

Study sample size characteristics

StudyPopulation TypeSample Size (n)WomenAge (yr) BMI (kg/m2)eGFR Cr 
(ml/min per 1.73 m2)HTNDMUMOD Indexed to UCr (mg/g Cr) UMOD Unindexed (μg/ml)
CoLausNonisolate urban507753.5 (2716)53.3±10.725.7±4.590.1± 19.536.0 (1830)4.5 (229)18.4 (3.6–46.7)25.8 (4.9–73.7)
Croatia-KorculaIsolate88763.7 (565)56.3±13.928.0±4.191.3±2955.9 (496)14.2 (126)6.4 (1.37–27.98)6.9 (2.28–26.85)
Croatia-SplitNonisolate urban48856.6 (276)49±14.726.9±4.295.6±23.835.2 (172)3.2 (16)20.6 (3.54–48.82)28.6 (5.05–88.68)
Framingham Heart StudyNonisolate urban264053.2 (1404)58.4±9.627.9±5.187.5±2540.0 (1055)9.4 (249)9.5 (0.3–27)7.42 (0.30–33)
INGI-CarlantinoIsolate36056.9 (205)48.1±20.426.7±5.994.8±25.740.4 (122)10.0 (29)6.7 (1.44–29.43)5.09 (0.97–20.74)
INGI-Val BorberaIsolate143255.7 (797)54.1±18.325.9±4.588.9±22.441.4 (593)6.6 (95)8 (1.54–34.54)6.75 (1.52–30.37)
  • Data are presented as mean±SD for continuous variables, % (n) for categorical variables, or median (5th percentile, 95th percentile). BMI, body mass index; Cr, creatinine; HTN, hypertension; DM, diabetes mellitus; UCr, urine creatinine.