Table 2.

Echocardiographic parameters and eGFR at baseline and 1 year and changes over 1 year

VariableBaseline1 YearChanges over 1 YearP Value
eGFR (ml/min per 1.73 m2)30.9±15.428.5±17.0−2.0 (−5.0, 0.0)<0.001
LV mass index (g/m2)105±32112±346.4 (0.6, 13.1)<0.001
LV volume index (ml/m2)42.8±11.143.9±11.80.9 (−1.5, 3.6)0.004
LV ejection fraction (%)70.0±6.869.0±6.9−1.0 (−6.0, 3.0)0.02
Midwall FS (%)17.7±2.317.4±2.6−0.3 (−1.9, 0.9)0.004
LAVi (ml/m2)30.6±12.635.3±13.74.8 (2.1, 7.7)<0.001
E (cm/s)81.2±21.582.7±21.91.0 (−9.0, 12.0)0.2
A (cm/s)87.2±22.388.8±24.31.0 (−7.0, 12.0)0.1
E/A0.97±0.31.00±0.50 (−0.1, 0.1)0.4
Sm (cm/s)9.0±1.98.4±2.0−0.5 (−1.5, 0.5)<0.001
Em (cm/s)9.7±2.89.0±2.6−0.5 (−1.5, 0.5)<0.001
Am (cm/s)11.6±2.311.3±2.3−0.5 (−1.5, 1.0)0.06
E/Em9.0±3.49.7±3.80.7 (−0.5, 2.0)<0.001
  • Continuous data are expressed as mean±SD. Changes over 1 year expressed as median (IQR). FS, fractional shortening; A, peak late transmitral flow velocity; E, peak early transmitral flow velocity; E/A, ratio of early to late transmitral flow velocity.