Table 3.

Association of rs12917707genotypes with urinary uromodulin levels in the six cohorts

CohortUMOD Indexed to UCr (μg/g Cr)Sample Size (n)Total Analyzed Sample Size (n)P Value in 
Each Cohorta
TTTGGGTTTGGG
CoLaus13.90±8.9218.74±13.0822.80±17.271951472341050772.31E-26
Croatia-Korcula4.83±3.638.07±8.169.97±10.83122076558744.97E-03
Croatia-Split12.80±4.9717.43±10.0326.09±16.83111233474819.27E-10
Framingham Heart Study5.27 (4.35)8.98±7.5312.60±11.88103851168926437.37E-25
INGI-Carlantino5.67±6.259.00±8.4911.13±15.2131082203416.08E-02
INGI- Val Borbera6.21±4.3110.27±10.8612.43±11.8926319102813731.50E-04
  • Data are presented as mean±SD unless otherwise indicated. UCr, urine creatinine; Cr, creatinine.

  • a The meta P value for the six cohorts is 2.41E-58.