Table 2.

Association of African-American race with hospitalized AKI

HR for African-American Race (95% CI)P Value
Unadjusted1.27 (1.08 to 1.49)0.004
Model 1: adjusted for demographics1.50 (1.27 to 1.77)<0.001
Model 2: model 1+CV risk factors and kidney function1.20 (1.01 to 1.43)0.04
Model 3: model 2+APOL1 risk alleles1.28 (1.06 to 1.55)0.01
Model 4: model 2+time-varying hospitalizations1.19 (1.00 to 1.42)0.04
Model 5: model 4+insurance1.11 (0.91 to 1.34)0.30
Model 6: model 5+income1.09 (0.89 to 1.32)0.40
  • Models include demographics (age and sex), cardiovascular (CV) risk factors (diabetes, hypertension, prevalent coronary heart disease, body mass index>30 kg/m2, uric acid, current smoking, and former smoking), kidney function (ACR [log 8-fold] and eGFR (knot at 60 ml/min per 1.73 m2), APOL1 risk alleles (two high-risk variants [yes or no]), time-varying hospitalizations (number of hospitalizations since baseline), insurance (yes or no), and income (<$12,000, $12,000–$24,999, $25,000–$49,999, and >$50,000).