Table 1.

Baseline characteristics of the healthy control and SIAD patient groups

CharacteristicSIAD Group (n=50)Control Group (n=10)
Age (yr)59.8±12.337.8±14.1a
Serum sodium (mmol/L)125±4137±2 b
Serum osmolality (mOsM/kg H2O)259±8283±4b
Urine osmolality (mOsM/kg H2O)509 (391, 691)570 (456, 718)
Urine sodium (mmol/L)95 (67,130)83 (37, 126)
Serum uric acid (mg/dl)3.4±0.83.6±0.6
Plasma copeptin (pmol/L)8.4 (4.2, 36)3.4 (2.9, 6.9)a
Plasma AVP (pmol/L)2.8 (1.5, 4.8)1.3 (0.8, 2.6)b
Mean arterial pressure (mmHg)88 (79, 92)81 (74, 87)
Heart rate (beats/min)72 (66, 82)72 (63, 85)
  • Data are expressed as mean±SD or median (IQR).

  • a P<0.05 for comparison of the respective SIAD subgroup with the healthy control group (Mann–Whitney U test).

  • b P<0.01 for comparison of the respective SIAD subgroup with the healthy control group (Mann–Whitney U test).