Table 3.

Adjusted IRRs for combined cancer outcomes in PKD versus non-PKD kidney transplant recipients

CharacteristicAll CancersAll Cancers, Excluding Kidney and Skina
Multivariate IRR (95% CI)bP ValueMultivariate IRR (95% CI)bP Value
PKD0.84 (0.77 to 0.91)<0.0010.83 (0.75 to 0.91)<0.001
Age at transplantation<0.001<0.001
 0–19 yr0.46 (0.39 to 0.55)0.57 (0.47 to 0.67)
 20–34 yr0.52 (0.47 to 0.57)0.54 (0.48 to 0.60)
 35–49 yrReferenceReference
 50–64 yr2.06 (1.93 to 2.19)2.15 (2.01 to 2.31)
 ≥65 yr3.22 (2.97 to 3.49)3.53 (3.23 to 3.86)
Female sex0.75 (0.71 to 0.79)<0.0010.80 (0.76 to 0.85)<0.001
Race/ethnicity<0.001<0.001
 White, non-HispanicReferenceReference
 Black, non-Hispanic0.94 (0.88 to 1.00)0.94 (0.88 to 1.02)
 Hispanic0.63 (0.58 to 0.69)0.64 (0.59 to 0.71)
 Asian/Pacific Islander0.66 (0.58 to 0.74)0.70 (0.61 to 0.79)
Duration of dialysis0.0370.27
 0–6 moReferenceReference
 >6–24 mo1.06 (0.98 to 1.14)1.09 (1.00 to 1.18)
 >24–48 mo1.05 (0.97 to 1.13)1.07 (0.98 to 1.17)
 >48 mo1.15 (1.05 to 1.26)1.10 (1.00 to 1.21)
 Missing mo1.06 (0.95 to 1.19)1.08 (0.95 to 1.22)
Time since transplant<0.001<0.001
 <1 yrReferenceReference
 1 to <3 yr1.06 (0.98 to 1.15)1.10 (1.00 to 1.20)
 3 to <5 yr1.18 (1.08 to 1.29)1.20 (1.10 to 1.32)
 >5 yr1.72 (1.60 to 1.86)1.73 (1.59 to 1.89)
  • a These analyses exclude kidney cancers, RCCs, melanomas, and nonepithelial skin cancers.

  • b Adjusted for factors in this table.