Table 2.

Echocardiographic standard and speckle-tracking deformation parameters of rats stratified for experimental groups

VariableControl EarlyAdenine Nephropathy Early5/6 Nephrectomy EarlyControl LateAdenine Nephropathy Late5/6 Nephrectomy Late
Heart rate (beats/min)306±32314±31309±18310±23308±28307±18
LVIDs (cm)0.33±0.080.4±0.090.37±0.080.35±0.050.42±0.040.48±0.08a
LVIDd (cm)0.63±0.150.72±0.150.65±0.080.67±0.050.69±0.080.77±0.12
IVSs (cm)0.18±0.030.28±0.04a0.29±0.05a0.19±0.020.35±0.13b0.4±0.05a
IVSd (cm)0.17±0.030.23±0.05b0.26±0.05a0.18±0.020.29±0.07b0.32±0.05a
LVPWs (cm)0.27±0.050.27±0.050.3±0.060.27±0.050.39±0.05a0.38±0.04a
LVPWd (cm)0.19±0.020.27±0.05b0.28±0.04a0.22±0.040.31±0.02c0.31±0.02c
SV (ml)0.26±0.040.26±0.020.24±0.020.26±0.010.23±0.03b0.22±0.03a
SC peak G−24±3.5−18.5±1.8b−18.4±2.6b−22.9±3.4−17±3.2a−15.2±1.6a
SC peak S−23.2±3.2−17.6±1.6b−16.4±3.8b−21.1±3.4−14±5.3b−13.6±2b
SR peak G30.5±5.916.8±3.3c16.1±3.4c29.9±6.312.8±4.2c12.2±3.7c
SrC peak S−6.2±0.8−5.3±0.7−4.7±0.2a−6.1±1−4.8±0.9−4.1±1a
SrC peak E6.2±0.566.2±1.14.7±2.36.4±14.1±2.33.9±2.3
SrR peak S6.7±1.24.7±1b4.6±1.5b7.1±1.25±1.7b4.7±0.6b
SrR peak E−7±1.1−5.2±0.9b−3.8±1.3c−7.3±0.8−5.2±1.6b−4.6±1.1a
  • Values are expressed as the mean±SD. LVIDs and LVIDd, left ventricular end-systolic and end-diastolic diameter; IVSs, septal thickness end-systolic; IVSd, septal thickness end-diastolic; LVPWs, left ventricular posterior wall thickness end-systolic; LVPWd, left ventricular posterior wall thickness end-diastolic; SV, stroke volume; SC peak G, strain circumferential global peak value; SC peak S, strain circumferential peak systolic value; SR peak G, strain radial peak global; SrC peak S, strain rate circumferential peak systolic value; SrC peak E, strain rate circumferential diastolic peak E; SrR peak S, strain rate radial systolic peak value; SrR peak E, strain rate radial diastolic peak E.

  • a P<0.01 versus control.

  • b P<0.05 versus control.

  • c P<0.001 versus control.