Table 3.

Longitudinal mixed-effects model for future eGFR using HtTKV as baseline predictor (class 1 and class 2 patients)

VariableClass 1Class 2 (A and B)
Estimate (95% CI)P ValueEstimate (95% CI)P Value
Intercept35.87 (20.31 to 51.42)<0.00122.78 (−13.64 to 59.19)0.21
Sex (reference is male)−0.95 (−2.89 to 0.99)0.34−2.65 (−8.09 to 2.79)0.33
Age at HtTKV0 (yr)−0.18 (−0.28 to −0.08)<0.001−0.07 (−0.35 to 0.20)0.59
eGFR at HtTKV0 (ml/min per 1.73 m2)0.90 (0.85 to 0.94)<0.0010.86 (0.71 to 1.00)<0.001
Log2(HtTKV0) (ml/m)−1.89 (−3.00 to −0.79)<0.001−0.90 (−3.99 to 2.19)0.56
Years from HtTKV07.65 (3.39 to 11.92)<0.001−0.81 (−9.30 to 7.68)0.85
Sex, years from HtTKV0 (interaction)−0.35 (−0.85 to 0.16)0.180.21 (−0.99 to 1.41)0.73
Age at TKV, years from HtTKV0 (interaction)0.03 (0.002 to 0.055)0.030.03 (−0.02 to 0.09)0.21
eGFR at HtTKV, years from HtTKV0 (interaction)−0.004 (−0.017 to 0.009)0.550.05 (0.02 to 0.08)0.004
Log2(HtTKV), years from HtTKV0 (interaction)−1.15 (−1.46 to −0.85)<0.001−0.65 (−1.36 to 0.06)0.07