Table 5.

Longitudinal mixed-effects model for future eGFR using classification as baseline predictor (class 1 patients)

VariableEstimate (95% CI)P Value
Intercept21.18 (9.75 to 32.61)0.003
Sex (reference is male)−1.26 (−3.65 to 1.12)0.30
Age at HtTKV0 (yr)−0.26 (−0.40 to −0.11)<0.001
eGFR at HtTKV0 (ml/min per 1.73 m2)0.90 (0.85 to 0.95)<0.001
Subclass 1Ba0.58 (−3.60 to 4.76)0.79
Subclass 1Ca−1.14 (−5.37 to 3.08)0.6
Subclass 1Da−1.93 (−6.63 to 2.76)0.42
Subclass 1Ea−6.26 (−11.91 to −0.62)0.03
Years from HtTKV0−0.23 (−3.42 to 2.96)0.9
Sex, years from HtTKV0 (interaction)0.19 (−0.42 to 0.81)0.54
Age at HtTKV, years from HtTKV0 (interaction)−0.02 (−0.06 to 0.02)0.32
eGFR at HtTKV, years from HtTKV0 (interaction)0.00 (−0.02 to 0.01)0.9
Subclass 1B,a years from HtTKV0 (interaction)−1.33 (−2.44 to −0.23)0.02
Subclass 1C,a years from HtTKV0 (interaction)−2.63 (−3.74 to −1.51)<0.001
Subclass 1D,a years from HtTKV0 (interaction)−3.48 (−4.73 to −2.23)<0.001
Subclass 1E,a years from HtTKV0 (interaction)−4.78 (−6.35 to −3.20)<0.001
  • a Reference is subclass 1A. Patients were subclassified based on HtTKV ellipsoid.