Table 1.

List of pathways significantly enriched in cell death genes

FunctionGenesP Value
Renal necrosis/cell death
 Cell death of kidney cellsBCL10, CLU, PSEN1, TNFRSF1B0.001
 Apoptosis of kidney cellsCLU, TNFRSF1B0.004
 Necrosis of kidney cellsTNFRSF1B0.01
 Apoptosis of renal tubular epithelial cellsCLU0.03
Opthalmic disease
 Opthalmic disorderATXN7, CLU, HTR2A, POLB, PSEN1, SNCA, SOD1<0.001
 KeratitisPOLB, PSEN10.001
 ConjunctivitisCLU, HTR2A0.002
 Retinal degenerationATXN7, CLU, SNCA0.002
 Ocular cicatrical pemphigoidCLU0.003
 Lattice corneal dystrophy type ICLU<0.01
 Gelationous drop-like corneal dystrophyCLU<0.01