Table 3.

Diagnostic performance of US

Diagnostic Criterion/Study CohortAffectedUnaffectedSENSPECPPVNPV
16–29 yr3758
 ≥1 renal cysta
  Present3690.9730.8450.8000.980
  ref. 190.8930.9710.9660.908
 ≥2 renal cystsa
  Present3630.9730.9480.9230.982
  ref. 190.8480.9940.9920.877
≥3 renal cystsa,b
  Present3610.9730.9830.9730.983
  ref. 190.8171.0001.0000.855
 ≥4 renal cystsa
  Present3610.9730.9830.9730.983
 ≥2 cysts in each kidney
  Present3600.9731.0001.0000.983
30–40 yr3624
 ≥1 renal cysta
  Present3641.0000.8330.9001.000
  ref. 190.9800.9480.9400.983
 ≥2 renal cystsa
  Present3621.0000.9170.9471.000
  ref. 190.9640.9830.9790.970
 ≥3 renal cystsa,b
  Present3621.0000.9170.9471.000
  ref. 190.9551.0001.0000.964
 ≥4 renal cystsa
  Present3601.0001.0001.0001.000
 ≥2 cysts in each kidney
  Present3601.0001.0001.0001.000
  ref. 190.8281.0001.0000.875
  • a Total number of cysts in both kidneys.

  • b Commonly used US diagnostic criterion for at-risk subjects of unknown gene type.