Table 2.

Baseline characteristics of REGARDS Study participants not taking statins without a history of ASCVD, diabetes, AF, or HF and with LDL-C between 70 and 189 mg/dl

Baseline CharacteristicsParticipants with CKD
eGFR<60 ml/min per 1.73 m2 or ACR≥30 mg/geGFR<60 ml/min per 1.73 m2ACR≥30 mg/g
Participants, n1110466770
ASCVD Pooled Cohort risk equation components
 Age (yr), mean (SD)66.3 (7.7)69.0 (7.1)65.0 (7.7)
 Blacks, n (%)516 (46.5)190 (40.8)394 (51.2)
 Men, n (%)465 (41.9)181 (38.8)345 (44.8)
 Current smoking, n (%)198 (17.8)53 (11.4)168 (21.8)
 Antihypertensive medication, n (%)605 (54.5)303 (65.0)389 (50.5)
 Systolic BP (mmHg), mean (SD)131.2 (18.1)129.7 (17.2)133.4 (18.8)
 Total cholesterol (mg/dl), mean (SD)203.3 (31.0)201.9 (30.5)203.5 (31.0)
 HDL-C (mg/dl), mean (SD)53.0 (17.4)52.1 (17.0)53.4 (17.7)
Other variables
 Region of residence, n (%)
  Stroke buckle208 (18.7)84 (18.0)147 (19.1)
  Stroke belt397 (35.8)165 (35.4)278 (36.1)
  Other contiguous United States505 (45.5)217 (46.6)345 (44.8)
 LDL-C (mg/dl), mean (SD)125.3 (27.1)123.9 (27.3)125.6 (27.0)
Renal parameters
 eGFR (ml/min per 1.73 m2), mean (SD)73.7 (24.5)49.5 (9.7)85.5 (22.8)
 ACR (mg/g), median (25th to 75th percentile)42.4 (12.4–80.5)9.1 (4.6–35.3)60.5 (40.4–110.9)
  • The stroke buckle includes North Carolina, South Carolina, and Georgia. The stroke belt includes the remaining parts of the stroke buckle states along with Tennessee, Mississippi, Alabama, Louisiana, and Arkansas.