Table 4.

Association between RHF at health screening and risk of disease development

MorbiditiesCase Per Person-YrIncidence DensityaaHR (95% CI)b
Hypertensionc1091/145,949797.71.30 (1.01 to 1.67)
Diabetesc3578/192,7961855.81.17 (0.91 to 1.51)
Cardiovascular diseasesc3849/227,7841689.81.17 (1.01 to 1.35)
Chronic renal disordersc,d366/216,478169.11.31 (0.86 to 2.00)
  • eGFR using the CKD-EPI equation above the age-, sex-, muscle mass-, and history of diabetes and/or hypertension medication-adjusted 95th percentile (details in Concise Methods).

  • a Incidence density (per 100,000 person-yr).

  • b aHR and 95% CI of the participants with RHF compared with those without RHF determined by the Cox proportional hazards model adjusted for possible confounding variables at baseline, such as age, sex, smoking, regular exercise, regular alcohol ingestion, history of diabetes and/or hypertension medication, BMI, systolic BP, FSG, serum triglyceride, serum HDL-cholesterol, and albuminuria (details in Concise Methods).

  • c Morbidities diagnosed at baseline or within 12 mo after health screening were excluded (details in Concise Methods).

  • d Definition in Concise Methods.