Table 3.

Association of LBM with BMI and RHF

LBMa QuartilesEstimated Mean BMIb (95% CI)RHF, %OR for RHFc (95% CI)
1st21.7 (21.6 to 21.7)20.9 (20.8 to 21.0)411/9939 (4.1%)Reference
2nd23.5 (23.5 to 23.6)22.5 (22.4 to 22.6)417/10,059 (4.1%)0.91 (0.78 to 1.05)
3rd24.8 (24.7 to 24.9)23.7 (23.6 to 23.8)508/10,108 (5.0%)1.07 (0.93 to 1.25)
4th26.8 (26.7 to 26.8)25.9 (25.8 to 26.0)677/10,143 (6.7%)1.31 (1.11 to 1.54)
  • eGFR using the CKD-EPI equation above the age-, sex-, muscle mass-, and history of diabetes and/or hypertension medication-adjusted 95th percentile (details in Concise Methods).

  • a LBM was measured by bioimpedance analysis and classified into sex-specific quartile groups.

  • b Estimated by the general linear model and adjusted for age, smoking, regular exercise, and regular alcohol ingestion. P for trend<0.001 in both men and women.

  • c OR by multivariate logistic regression analysis adjusted for age, sex, smoking status, regular exercise, regular alcohol intake, history of therapy for diabetes and/or hypertension, BMI, systolic BP, FSG, serum triglyceride, serum HDL-cholesterol, and albuminuria. P for trend<0.001.