Table 1.

Baseline patient characteristics and outcomes

CharacteristicDeath or DialysisNeither Death Nor DialysisP Value
All patients217475
Men131 (60)292 (61)0.80
Age (yr)71 (59–78)61 (51–70)<0.001
Body mass index (kg/m2)26 (23–31)27 (24–31)0.09
Race0.79
 Black or African American24 (11)61 (13)
 Other/unknown/missing21 (10)43 (9)
 White or Caucasian172 (79)371 (78)
Chronic comorbidities
 CKD29 (13)31 (7)0.005
 Diabetes mellitus67 (31)128 (27)0.32
 Congestive heart failure43 (20)72 (15)0.15
 Coronary artery disease67 (31)136 (29)0.59
 Hypertension134 (62)271 (57)0.28
 Chronic obstructive pulmonary disease56 (26)97 (20)0.12
 Cancer64 (29)110 (23)0.09
 Liver disease8 (4)22 (5)0.69
Reason for ICU admission
 Respiratory126 (58)168 (35)<0.001
 Surgery46 (21)192 (40)<0.001
 Cardiovascular75 (35)155 (33)0.66
 Sepsis46 (21)79 (17)0.17
 Cerebrovascular25 (12)41 (9)0.26
 Trauma10 (5)43 (9)0.05
 Burn7 (3)7 (1)0.15
 Other38 (18)82 (17)>0.99
Enrollment serum creatinine (mg/dl)1.0 (0.71–1.4)0.9 (0.7–1.1)0.001
APACHE III nonrenal70 (50–93)54 (40–75)<0.001
Maximum KDIGO stage within 72 h<0.001
 No AKI68 (31)242 (51)
 KDIGO 178 (36)160 (34)
 KDIGO 246 (21)70 (15)
 KDIGO 325 (12)3 (1)
Outcomes
 ICU length of stay (d)9 (5–18)6 (4–12)<0.001
 Hospital length of stay (d)15 (9–26)13 (8–21)0.11
 In-hospitala RRT40 (18)0 (0)<0.001
 In-hospitala mortality108 (50)0 (0)<0.001
 Postdischarge RRT2 (1)0 (0)0.10
 Postdischarge mortality92 (42)0 (0)<0.001
  • Values shown as N (%) and median (interquartile range).

  • a Truncated at 30 days.