Table 1.

Clinical characteristics discovery and replication cohort

VariableDiscovery CohortReplication Cohort
Patients (n=214)Controls (n=149)Patients (n=100)Controls (n=205)
RaceSouth AsianSouth AsianWhite EuropeanWhite European
Male-to-female ratio2:12.3:11.6:11.6:1
Median age at onset (range) (yr)3 (1–9.5)NA3.2 (1–12)NA
Median age at enrollment (range) (yr)NA26 (19–49)NA68 (40–86)
  • NA, not applicable.