Table 2.

Main baseline clinical data in the Turin and Cagliari patient cohorts

CharacteristicTurinCagliariAll PatientsP Value for Turin versus Cagliari
Pregnancies (n)336168504
Baseline hypertension (%)19.6 (66)42.9 (72)27.4 (138)<0.001
Baseline proteinuria (g/d)0.13 (0.01–14.6)0.14 (0.01–5.38)0.13 (0.01–14.6)0.11
Proteinuria (class)0.84
 <0.371.1 (239)73.1 (117)71.8 (356)
 ≥0.3 to <0.58.0 (27)7.5 (12)7.9 (39)
 0.5–18.9 (30)6.9 (11)8.3 (41)
 1–38.3 (28)10.0 (16)8.9 (44)
 ≥33.6 (12)2.5 (4)3.2 (16)
Median GFR (ml/min)
 CKD-EPI120 (15–186)112 (6–145)118 (6–186)<0.001
 Cockcroft–Gault121 (19–396)102 (14–302)114 (14–396)<0.001
Median serum creatinine (mg/dl)0.62 (0.3–3.80)0.70 (0.38–7.9)0.64 (0.3–7.9)<0.001
CKD stage<0.001
 178.9 (265)62.5 (105)73.4 (370)
 212.8 (43)26.2 (44)17.3 (87)
 36.8 (23)8.3 (14)7.3 (37)
 4–51.5 (5)3 (5)2 (10)
Main cause of CKD (%)<0.001
 Glomerular15.517.916.3
 Interstitial52.7938.1
 ADPKD4.56.55.2
Systemic disease (%)<0.001
 SLE-collagen diseases4.7199.5
 Diabetic nephropathy (type 1)3.310.15.6
 Kidney graft3.63.63.6
  • Data are presented as % (n) or median (range) unless otherwise specified. CKD-EPI, Chronic Kidney Disease in Epidemiology Collaboration; ADPKD, autosomic dominant polycystic kidney disease.