Table 1.

Participant characteristics at randomization (following the 1-month run-in period)

Age (yr)6.9±3.16.9±3.6
Boys (%)11 (73)10 (67)
Body weight (kg)31±1430±16
Disease duration (yr)2.0±2.52.7±2.4
Median no. of relapses (range)a2 (2–7)3 (2–8)
Steroid toxicity (%)b00
Prednisone dose (mg/kg per day)0.60±0.470.57±0.42
ARB/ACEI use, n ( %)2 (13%)0
Urinary protein (mg/m2 per day)76±4884±39
Serum albumin (g/dl)4.0±0.43.8±0.3
Serum cholesterol (mg/dl)172±20164±20
Serum creatinine (mg/dl)0.41±0.10.40±0.2
  • Values are reported as means±SDs for quantitative variables (units) and as absolute (n) and relative (%) frequencies for qualitative variables. ARB/ACEi, angiotensin-receptor blockers or angiotensin-converting enzyme inhibitors.

  • a Number of relapses before the development of steroid dependence.

  • b See Supplemental Table 1 for definitions.