Table 3.

Univariate HRs of graft loss and death among HIV+ recipients

DemographicsRisk of Graft LossRisk of Death
HR (95% CI)P ValueHR (95% CI)P Value
Recipient characteristics
 Age≥50 yr1.16 (0.83 to 1.62)0.382.05 (1.36 to 3.09)<0.001
 Male sex0.91 (0.61 to 1.35)0.640.88 (0.53 to 1.46)0.62
 African American race1.34 (0.92 to 1.94)0.130.78 (0.51 to 1.22)0.28
 BMI (kg/m2)
  Normal weightReferenceReference
  Underweight1.14 (0.36 to 3.62)0.832.13 (0.66 to 6.92)0.21
  Overweight0.73 (0.49 to 1.09)0.120.56 (0.32 to 0.96)0.04
  Obese0.79 (0.47 to 1.32)0.370.60 (0.30 to 1.23)0.31
 Peak PRA>80%1.79 (1.01 to 3.16)0.051.62 (0.78 to 3.36)0.19
 HCV infection2.41 (1.73 to 3.38)<0.0012.85 (1.89 to 4.31)<0.001
 Antithymocyte globulin induction0.94 (0.64 to 1.37)0.741.14 (0.71 to 1.82)0.59
 CNI maintenance regimen0.60 (0.37 to 0.96)0.030.61 (0.34 to 1.10)0.10
 Acute rejection within 1 yr1.56 (1.05 to 2.31)0.030.62 (0.33 to 1.16)0.14
 Maintenance steroids1.15 (0.76 to 1.72)0.511.14 (0.67 to 1.94)0.63
Donor characteristics
 Age≥50 yr1.02 (0.69 to 1.49)0.931.09 (0.68 to 1.75)0.73
 Race
CaucasianReferenceReference
African American0.89 (0.60 to 1.34)0.590.60 (0.34 to 1.05)0.07
Other1.24 (0.80 to 1.91)0.331.10 (0.64 to 1.88)0.90
 Living donor0.45 (0.30 to 0.68)<0.0010.49 (0.29 to 0.83)0.01
 Expanded criteria donor1.51 (0.90 to 2.54)0.121.34 (0.73 to 2.57)0.33
 Donor after cardiac death0.94 (0.51 to 1.73)0.830.78 (0.34 to 1.79)0.56
 CIT>10 ha1.69 (1.01 to 2.82)0.051.59 (0.82 to 3.11)0.17
  • a Among deceased donor transplants only.