Table 1.

Demographic and clinical characteristics of participants who died during follow-up according to cause of death (n=81,064)

Participant CharacteristicsAll ParticipantsCVDInfectionCancerOtheraMissingP Value
N81,064 (100)24,494 (30.2)3274 (4.0)25,882 (31.9)22,631 (27.9)4783 (5.9)
Age, yr83 (75–89)83 (73–90)73 (63–81)80 (68–88)78 (65–86)<0.001
Men40,606 (50.1)11,866 (48.4)1544 (47.2)13,664 (52.8)11,056 (48.9)2476 (51.8)<0.001
Aboriginal1790 (2.2)368 (1.5)129 (3.9)420 (1.6)773 (3.4)100 (2.1)<0.001
Social assistance2923 (3.6)505 (2.1)169 (5.2)809 (3.1)1255 (5.5)185 (3.9)<0.001
Rural residence11,059 (13.6)3176 (13)429 (13.1)3702 (14.3)3070 (13.6)682 (14.3)<0.001
Comorbidities
 Diabetes22,888 (28.2)7819 (31.9)1053 (32.2)5859 (22.6)6785 (30)1372 (28.7)<0.001
 Hypertension55,871 (68.9)19,966 (81.5)2358 (72)15,240 (58.9)14,989 (66.2)3318 (69.4)<0.001
 Charlson scoreb4 (2–6)4 (2–6)9 (8–10)3 (2–6)4 (2–8)<0.001
eGFR, ml/min per 1.73 m2<0.001
  ≥60 without proteinuriac31,323 (38.6)7655 (31.3)904 (27.6)11,927 (46.1)8976 (39.7)1861 (38.9)
  ≥60 with proteinuria15,278 (18.9)3169 (12.9)770 (23.5)6146 (23.7)4211 (18.6)982 (20.5)
 45–5915,673 (19.3)5763 (23.5)674 (20.6)4141 (16)4176 (18.5)919 (19.2)
 30–4412,268 (15.1)5054 (20.6)588 (18)2606 (10.1)3338 (14.7)682 (14.3)
 15–296522 (8.1)2853 (11.6)338 (10.3)1062 (4.1)1930 (8.5)339 (7.1)
  • a Other includes 5236 deaths caused by neurologic diseases and dementias, 4086 deaths caused by chronic lung disease, 3500 deaths caused by suicides and accidents, 3076 deaths caused by digestive diseases, 1583 deaths caused by diabetes, and an additional 5150 (6.4%) other deaths.

  • b Charlson score includes AIDS/HIV, metastatic cancers, nonmetastatic cancers, CVA, chronic obstructive lung disease, dementia, diabetes, heart failure, mild liver disease, moderate/severe liver disease, myocardial infarction, paraplegia, peptic ulcer, peripheral vascular disease, and rheumatologic disease. The median and interquartile ranges are presented.

  • c Proteinuria is defined as urine dipstick trace or greater, albumin-to-creatinine ratio≥3 mg/mmol, or protein-to-creatinine ratio≥15 mg/mmol.