Table 2.

APOL1 genotype distribution among patients with HIVAN, HIV-positive patients with CKD, HIV-negative patients with CKD, and controls

GenotypeHIV-Positive Patients and ControlsHIV-Negative Patients and Controls
HIVANaCKDbHIV-Positive ControlsCKDcPopulation Controls
0 risk alleles
 G0/G02 (5.3)22 (56.4)34 (63.0)25 (64.1)36 (66.7)
1 risk allele6 (15.8)11 (28.2)18 (33.3)13 (33.3)17 (31.5)
 G0/G15 (13.2)4 (10.3)4 (7.4)6 (15.4)7 (13.0)
 G0/G21 (2.6)7 (17.9)14 (25.9)7 (17.9)10 (18.5)
2 risk alleles30 (78.9)6 (15.4)2 (3.7)1 (2.6)1 (1.9)
 G1/G18 (21.0)2 (5.1)0 (0.0)0 (0.0)0 (0.0)
 G1/G219 (50.0)2 (5.1)0 (0.0)1 (2.6)0 (0.0)
 G2/G23 (7.9)2 (5.1)2 (3.7)0 (0.0)1 (1.9)
Total3839543954
  • Data are given as n (%). The distribution of APOL1 genotypes and fractions with one or two risk alleles for the study groups is shown.

  • a One patient did not pass genotyping.

  • b The single HIV-positive patient with CKD carrying the G1+M (A-G-I) haplotype is excluded from this table and one patient did not pass genotyping.

  • c Two patients did not pass genotyping.