Table 1.

Electrolyte metabolism profile of WT and cav-1 KO mice

ParameterWT (n=8)cav-1 KO (n=8)
Body wt (g)21.5±0.322.2±0.7
Na+ intake (mg/g body wt)0.51±0.080.55±0.04
UNa+ (mg/g body wt)0.25±0.050.28±0.05 (P=0.37)
K+ intake (mg/g body wt)1.69±0.061.81±0.04
UK+ (mg/g body wt)0.87±0.051.17±0.04 (P<0.01)
Mg2+ intake (μg/g body wt)357±10379±10
UMg2+ (μg/g body wt)25.5±2.036.7±3.0 (P<0.02)
Ca2+ intake (μg/g body wt)161±10171±10
UCa2+ (μg/g body wt)4.53±0.315.31±0.33 (P=0.06)
  • Body wt, body weight; UCa2+, 24-hour urinary Ca2+ excretion; UK+, 24-hour urinary K excretion; UMg2+, 24-hour urinary Mg2+ excretion; UNa+ ,24-hour urinary Na excretion.