Table 1.

Baseline cohort characteristics

CharacteristicN (%) or median (IQR)N
Age (years)11.0 (7.4, 14.5)537
Male gender326 (61)537
Black race116 (22)537
Hispanic76 (14)531
Tanner stage514
 1307 (60)
 249 (10)
 342 (8)
 472 (14)
 544 (9)
Height Z-score−0.7 (−1.4, 0.1)523
Body mass index Z-score0.4 (−0.4, 1.2)521
eGFR (ml/min 1.73 m2)46.5 (34.4, 58.5)531
CKD stage531
 1/2119 (22)
 3325 (61)
 4/587 (16)
CKD duration (years)8.5 (4.4, 12.9)531
Glomerular etiology110 (20)537
Autoimmune disease14 (3)530
Prematurity65 (13)519
Walking difficulty64 (12)532
Medications537
Vitamin/mineral supplement122 (23)
Nutritional vitamin D supplement27 (5)
Activated vitamin D191 (36)
Phosphate binder102 (19)
Alkali therapy152 (28)
Growth hormone60 (11)
Diuretic34 (6)
Corticosteroid36 (7)
Albumin (g/dl)4.3 (4.1, 4.5)533
Corrected calcium (mg/dl)9.4 (9.1, 9.6)533
Phosphorus (mg/dl)4.5 (4.0, 5.0)525
Parathyroid hormone (pg/ml)48.2 (28.5, 83.1)379
25-hydroxyvitamin D [25(OH)D, ng/ml]28.3 (19.1, 35.1)388
Vitamin D deficiency [25(OH)D <20 ng/ml]105 (27)
FGF23 (RU/ml)131.2 (87.9, 197.9)388
  • IQR, interquartile range.