Table 2.

The relative hazard of all-cause and cardiovascular mortality by time-varying PRA category

Cox ModelPRA 0%PRA 1%–19%PRA 20%–79%PRA 80%–100%
All-cause mortality
 1Referent1.00 (0.96 to 1.03)1.05 (1.01 to 1.09)1.13 (1.08 to 1.18)
 2Referent1.03 (1.04 to 1.07)1.13 (1.09 to 1.18)1.26 (1.20 to 1.32)
 3Referent1.02 (0.99 to 1.06)1.11 (1.07 to 1.16)1.21 (1.15 to 1.27)
Cardiovascular mortality
 1aReferent1.01 (0.97 to 1.07)1.00 (0.97 to 1.07)1.09 (1.01 to 1.17)
 2Referent1.06 (1.00 to 1.11)1.12 (1.06 to 1.19)1.26 (1.17 to 1.36)
 3Referent1.05 (1.00 to 1.10)1.11 (1.05 to 1.18)1.21 (1.12 to 1.31)
  • Data are presented as HRs (95% CIs). Model 1 includes the PRA category. Model 2 includes the PRA category, age, sex, race, body mass index, and cause of ESRD. Model 3 includes the PRA category, age, sex, race, body mass index, cause of ESRD, dialysis modality, time from dialysis initiation to activation, activation era, multilisting, diabetes, peripheral vascular disease, and HCV.

  • a The omnibus test for this model did not reach statistical significance (P=0.15). The P value of the omnibus test in all other models was <0.001.