Table 2.

Serum creatinine, calcium, phosphate, and PTH levels in uremic rats with and without rapamycin

VariableControlAdenineAdenine and Rapamycin
Creatinine (mg/dl)0.6±0.041.2±0.12a1.4±0.2a
Calcium (mg/dl)9.7±0.38.3±0.99.9±0.4
Phosphate (mg/dl)7.7±0.210.4±0.7a12.8±0.5a,b
PTH (pg/ml)326±332064±213a1479±122a,b
Change in body weight (g)ND−38±9−35.7±11
  • Results are mean±SEM (n=9–12). Results represent data from three experiments combined. Body weights: n=5. ND, not determined.

  • a P<0.05 compared with control diet.

  • b P<0.05 compared with adenine diet.