Table 1.

Differences in AMD and aHUS overall risk scores

Groups ComparedMean Overall Risk
AMD risk
 aHUS R1210C carriers (n=13)44.8 ± 25.344.8 ± 25.3
 AMD cohort (n=259)67.3 ± 20.8
 Controls (n=191)44.3 ± 21.1
p-value0.0010.99
 Healthy R1210C carriers (n=16)49.9 ± 18.549.9 ± 18.5
 AMD cohort (n=259)67.3 ± 20.8
 Controls (n=191)44.3 ± 21.1
p-value0.0040.56
 R1210C AMD pedigrees (n=22)60.6 ± 23.860.6 ± 23.8
 AMD cohort (n=259)67.3 ± 20.8
 Controls (n=191)44.3 ± 21.1
p-value0.330.002
aHUS risk
 aHUS R1210C carriers (n=13)2.46 ± 1.052.46 ± 1.05
 R1210C AMD pedigrees (n=22)0.38 ± 0.59
 Healthy R1210C carriers (n=13)0.88 ± 0.81
p-value<0.001<0.001