Table 2.

Immune phenotype of study participants at enrolment

VariableRTRSCCRTRNoP Value
Lymphocyte count1135 (863–1658)1360 (1040–1728)0.15
Monocyte count500 (410–635)475 (413–600)0.58
Total (CD3+) T cell count945 (649–1339)1157 (785–1467)0.25
Gamma-delta T cell count33 (14–79)38 (13–97)0.77
Gamma-delta T cell percentage2.6 (1.5–5.5)3.0 (1.2–6.7)0.83
CD4+ T cell count567 (431–700)666 (474–836)0.13
CD4+ T cell percentage48 (39–61)49 (40–60)0.79
Treg (CD4+CD69-CD25hiCD127loFoxP3+) cell count16 (9–22)13 (9–19)0.51
Treg percentage (of CD4+ population)2.5 (1.8–3.6)2.3 (1.7–3.0)0.19
CD57+ percentage (of CD4+ population)11 (7–28)11 (6–18)0.35
CD8+ T cell count275 (132–410)284 (179–510)0.20
CD8+ T cell percentage22 (15–31)24 (16–32)0.61
CD8+CD57+ T cell count162 (48–282)146 (77–310)0.65
Naïve CD8+ T cell (percentage of CD8+)11 (4–33)15 (5–34)0.96
CD8+ TEm (percentage of CD8+)24 (14–39)22 (12–43)0.90
CD8+ TEMRA (percentage of CD8+)54 (29–73)42 (20–74)0.40
CD8+ TCm (percentage of CD8+)1 (0.4–4)1 (0.3–3)0.50
CD57+ percentage (of CD8+ population)67 (39–76)53 (36–70)0.18
>50% of CD8+ T cells CD57+ (‘CD57hi’ phenotype)36 (61)29 (50)0.21
NK cell (CD3-CD56+) count30 (16–109)43 (13–121)0.97
NK cell percentage3.5 (1.4–9.7)3.1 (1.0–9.1)0.70
CD19+ B cell count19 (8–44)19 (12–40)0.45
CD19+ B cell percentage1.7 (0.9–3.7)1.8 (0.9–2.9)0.38
  • Continuous variables are reported as median (IQR) while categorical variables are reported as number (percentage of column). Counts are reported as cells per microliter of blood, while percentages are reported as a fraction of the lymphocyte population, unless specified otherwise. Groups were compared by Mann–Whitney test.