Table 2.

Baseline characteristics at initiation (n=1,069,343)

Cause of ESRDMultiple MyelomaAOR, Multiple Myeloma
YesNo
N12,7031,056,640
Age, years
 <401.49.20.19 (0.17–0.23)
 40–643541.91 (Reference)
 ≥6563.648.91.35 (1.3–1.41)
Sex
 Men56.255.6a1 (Reference)a
 Women43.844.40.99 (0.95–1.02)
Race
 White76.465.41 (Reference)
 Black20.828.50.63 (0.61–0.66)
 Other2.86.10.41 (0.37–0.46)
Ethnicity
 Hispanic6.413.60.42 (0.39–0.46)
 Non-Hispanic93.686.51 (Reference)
Ischemic heart disease
 No86.176.31 (Reference)
 Yes13.923.70.39 (0.37–0.41)
Diabetes
 No82.547.71 (Reference)
 Yes17.552.30.19 (0.18–0.2)
Mode of RRT
 Hemodialysis96.991.41 (Reference)
 Peritoneal dialysis3.16.60.47 (0.42–0.52)
Initial vascular access (hemodialysis)
 Fistula3.613.91 (Reference)
 Graft1.53.61.67 (1.33–2.1)
 Catheter94.982.44.68 (4.12–5.31)
Nephrologist care, months
 >129.624.41 (Reference)
 ≤1290.475.63.29 (3.04–3.56)
eGFR, ml/min per 1.73 m2
 ≤1594.387.41 (Reference)
 >155.712.60.39 (0.37–0.42)
BMI, kg/m2
 <3078.766.31 (Reference)
 ≥3021.333.70.53 (0.51–0.56)
Albumin, g/dl
 ≥3.528.8351 (Reference)
 <3.571.2651.35 (1.29–1.41)
Hemoglobin, g/dl
 <936.325.61 (Reference)
 ≥963.774.40.52 (0.5–0.54)
  • Parameter estimates are presented as column percentages or odds ratios, with 95% confidence intervals in parentheses. As data fields for pre-dialysis vascular access for hemodialysis and nephrologist care before RRT were not available before the 2005 version of the Medical Evidence Report, these variables are provided for 59.1% of the study population. Missing data: initial hemodialysis access, 46.6%; prior nephrology care, 40.9%; eGFR, 0.6%; BMI, 1.4%; serum albumin, 24.5%; hemoglobin, 8.3%. P<0.001 unless otherwise indicated for comparisons of patients with and without multiple myeloma. BMI, body mass index; AOR, adjusted odds ratio (with logistic regression and age, sex, race, and ethnicity as adjustment factors).

  • a P≥0.05.