Fit Statistic | Model 1 | Model 2 (Model 1 + ln CFR) | ||
---|---|---|---|---|

Estimate/HR (95% CI) | P Value | Estimate/HR (95% CI) | P Value | |

Global chi squared | 31.5 | Reference | 40.5 | 0.003 |

Age, yr | 1.01 (0.97 to 1.06) | 0.53 | 1.01 (0.96 to 1.05) | 0.77 |

Overt CVD | 4.47 (1.26 to 15.94) | 0.02 | 4.75 (1.35 to 16.76) | 0.02 |

Ischemia + scar, % myocardium | 1.06 (1.03 to 1.09) | <0.001 | 1.04 (1.01 to 1.07) | 0.002 |

ln CFR (per 0.5-unit increase) | 0.01 (<0.01 to 0.15) | 0.002 |

Model 2 adds ln CFR to model 1. Overt cardiovascular disease (CVD) was defined as one or more of the following: prior myocardial infarction, stroke, percutaneous coronary intervention, coronary artery bypass, or peripheral arterial revascularization. HR, hazard ratio.