Table 3.

Allele and genotype frequencies of common variants of CFHR5 in patients with IgAN and healthy controls

VariantsAllele FrequenciesGenotype Frequencies
c.58+17 T>AATAA + ATTT
 IgAN140 (14.00%)860 (86.00%)15+110 (25.00%)375 (75.00%)
 HC163 (14.10%)989 (85.90%)7+149 (27.10%)420 (72.90%)
P value0.920.44
c.431–80 G>AAGAA + AGGG
 IgAN13 (1.30%)987 (98.70%)0+13 (2.60%)487 (97.40%)
 HC15 (1.30%)1137 (98.70%)0+15 (2.60%)561 (97.40%)
P value>0.99>0.99
c.434 G>AAGAA + AGGG
 IgAN13 (1.30%)987 (98.70%)0+13 (2.60%)487 (97.40%)
 HC15 (1.30%)1137 (98.70%)0+15 (2.60%)561 (97.40%)
P value>0.99>0.99
c.1147+24 T>GGTGG + GTTT
 IgAN332 (33.20%)668 (66.80%)61+210 (54.20%)229 (45.80%)
 HC364 (31.60%)788 (68.40%)49+266 (54.70%)261 (45.30%)
P value0.430.87
  • HC, healthy controls.