Table 2.

Adjusted association between selected metabolites and RR of impaired executive function in discovery cohort (n=141)

Adjusted RR (95% CI)
MetaboliteModel OneModel Two
4-hydroxyphenylacetate per SD increase in log1.19 (1.06 to 1.33)1.16 (1.03 to 1.32)
Phenylacetylglutamine per SD increase in log1.38 (1.12 to 1.68)1.39 (1.13 to 1.71)
Hippurate per SD increase in log1.23 (1.02 to 1.49)1.24 (1.03 to 1.50)
Prolyl-hydroxyproline per SD increase in log1.20 (1.05 to 1.36)1.20 (1.05 to 1.38)
  • Model 1 is adjusted for vintage and peritoneal dialysis (versus hemodialysis).

  • Model 2 is adjusted for age, education, language, stroke, vintage, and peritoneal dialysis.