Table 3.

Subgroup Analysis for the Association Between Acute Kidney Injury and Acute Myocardial Infarction

StratificationNumber of StudiesSettingaRelative Risk95% CII2, %P Value
AMI – setting
 CIN5-1.431.18 to 1.75480.93
 Peri-operative3-1.391.08 to 1.7747
 Other2-1.310.82 to 2.0955
AMI – recovery
 Complete recovery2CIN (1)1.140.87 to 1.4800.12
Peri-op (1)
Other (0)
 Partial or no recovery2CIN (1)1.551.16 to 2.070
Peri-op (1)
Other (0)
AMI – severity
 Mild AKI4CIN (2)1.451.28 to 1.65180.64
Peri-op (2)
Other (0)
 Moderate to severe AKI4CIN (2)1.531.27 to 1.840
Peri-op (2)
Other (0)
AMI – median proportion baseline CHF (min–max)
 0.04 (0–0.06)4CIN (0)1.421.19 to 1.69380.91
Peri-op (2)
Other (2)
 0.15 (0.10–0.17)3CIN (2)1.401.17 to 1.670
Peri-op (1)
Other (0)
AMI – median proportion baseline IHD (min–max)
 0.12 (0.10–0.72)3CIN (1)1.321.10 to 1.5720.44
Peri-op (2)
Other (0)
 1 (1–1)7CIN (4)1.451.23 to 1.7151
Peri-op (1)
Other (2)
AMI – median proportion baseline stroke (min–max)
 0.04 (0–0.06)4CIN (1)1.371.14 to 1.65620.49
Peri-op (2)
Other (1)
 0.10 (0.07–0.95)4CIN (3)1.591.08 to 2.3447
Peri-op (1)
Other (0)
AMI – median proportion baseline CKD (min–max)
 8.8 (0–0.18)5CIN (3)1.321.09 to 1.61430.45
Peri-op (2)
Other (0)
 0.28 (0.20–1)4CIN (2)1.471.23 to 1.7537
Peri-op (1)
Other (1)
  • AMI, acute myocardial infarction; CIN, contrast induced nephropathy; peri-op, peri-operative or intensive care unit.

  • a Number of studies is provided in brackets.