Table 1.

Characteristics of the study cohort, by age and whether patient received a predialysis fistula attempt

Baseline characteristics<65 yr≥65 yr
No AttemptAttemptP ValueNo AttemptAttemptP Value
n=795n=212n=1018n=275
Age, median (IQR)54 (44, 60)56 (47, 61)0.0775.3 (70, 81)76 (71, 80.1)0.81
Male, n (%)493 (62)141 (67)0.23613 (60)169 (62)0.71
Initiation of dialysis
 Predialysis care, n (%)
  Any531 (67)212 (100)<0.01733 (72)275 (100)<0.01
  ≥4 mo406 (51)199 (94)<0.01584 (57)268 (98)<0.01
  ≥12 mo301 (38)165 (78)<0.01468 (46)234 (85)<0.01
  Inpatient start535 (67)37 (18)<0.01720 (71)83 (30)<0.01
  ICU start166 (21)3 (1)<0.01210 (21)7 (3)<0.01
 eGFR, median (IQR)8.4 (6, 12.2)7.3 (5.6, 9.2)<0.019.3 (6.6, 12.7)8.8 (7.3, 10.8)0.11
 eGFR category, n (%)<0.01<0.01
  <10473 (60)167 (79)569 (56)181 (66)
  10–15181 (23)34 (16)285 (28)81 (30)
  >15125 (16)8 (4)143 (14)11 (4)
Comorbidities, n (%)
 Diabetes467 (59)132 (62)0.35527 (52)158 (58)0.09
 Coronary artery disease203 (26)55 (26)0.90475 (47)110 (40)0.05
 Congestive heart failure181 (23)31 (15)0.01398 (39)69 (25)<0.01
 Cerebrovascular disease78 (10)25 (12)0.40215 (21)50 (18)0.28
 Peripheral vascular disease107 (14)27 (13)0.78245 (24)42 (15)<0.01
 Cancer73 (9)16 (8)0.46274 (27)61 (22)0.11
BMI, median (IQR)27.3 (23.6, 32)29.7 (25.9, 35)<0.0126.2 (23, 30.4)27.2 (23.9, 31)0.03
Laboratory measurements
 Albumin, g/L, mean (SD)28.9 (7.5)32.4 (6.5)<0.0129.9 (6.9)33.1 (6)<0.01
 Bicarbonate, mmol/L, median (IQR)19 (16, 23)19 (16, 22)0.1720 (17, 24)20 (17, 23)0.41
 Calcium, mmol/L, mean (SD)2 (0.2)2.1 (0.2)<0.012.1 (0.2)2.2 (0.2)<0.01
 Creatinine, µmol/L, median (IQR)576 (423, 797)676 (557, 824)<0.01505 (380, 668)528 (436, 638)0.09
 Hemoglobin, g/L, mean (SD)92.9 (16.7)99.2 (16.7)<0.0195.5 (15.4)101.7 (15.7)<0.01
 Parathyroid hormone, pmol/L, median (IQR)268 (138, 474)282 (138, 418)0.59256 (141, 421)182 (110, 307)<0.01
 Phosphate, mmol/L, mean (SD)2 (0.7)2 (0.5)0.601.9 (0.6)1.7 (0.4)<0.01
 Urea, mmol/L, mean (SD)31.7 (12.1)32.9 (9.9)0.1833.3 (12)32.5 (9.9)0.37
  • IQR, interquartile range; ICU, intensive care unit.