Table 5.

Associations (HRs and 95% CIs) of FGF23 with first infection-related hospitalization for the 881 participants in a random subgroup with measurements of markers of mineral metabolism

ModelQuartile 1 <53.34 RU/ml, n=223Quartile 2 =53.34–70.34 RU/ml, n=228Quartile 3 =70.35–99.33 RU/ml, n=220Quartile 4 >99.33 RU/ml, n=210Per Doubling of FGF23
Model 1Reference1.25 (0.90 to 1.73)1.50 (1.08 to 2.08)2.96 (2.15 to 4.09)1.61 (1.43 to 1.81)
Model 2Reference1.10 (0.79 to 1.53)1.34 (0.96 to 1.88)2.19 (1.54 to 3.13)1.42 (1.24 to 1.63)
Model 3Reference1.07 (0.77 to 1.49)1.27 (0.91 to 1.79)2.07 (1.44 to 2.97)1.37 (1.19 to 1.57)
Model 4aReference1.04 (0.75 to 1.45)1.24 (0.88 to 1.75)2.02 (1.41 to 2.91)1.35 (1.17 to 1.55)
Model 4bReference1.04 (0.74 to 1.45)1.25 (0.89 to 1.75)1.99 (1.38 to 2.86)1.34 (1.17 to 1.55)
  • Model 1: age, race, and sex. Model 2: model 1, smoking status, BMI, diabetes, CHD, CHF, eGFR (cystatin C equation), and urine ACR. Model 3: model 2, albumin, CRP, and IL-6. Model 4a: model 3, calcium, phosphorus, 25(OH)D, iPTH, and 24,25(OH)2D. Model 4b: model 3, calcium, phosphorus, iPTH, and the VMR [24,25(OH)2D-to-25(OH)D ratio]. RU, relative unit.