Table 3.

Multivariate Cox regression model of the risk of death associated with cumulative (1 year) exposure to FO across systolic BP categories

VariablesHR (95% CI)
BP<130 FO normal1.19 (1.06 to 1.33)
BP<130 FO high1.94 (1.68 to 2.23)
BP=130–160, FO normal1.00 (Reference)
BP=130–160, FO high1.51 (1.35 to 1.69)
BP>160, FO normal1.18 (1.00 to 1.38)
BP>160, FO high1.62 (1.39 to 1.90)
Sex (1= man)1.09 (0.98 to 1.21)
Age, per yr1.03 (1.03 to 1.04)
Height, per cm1.00 (0.99 to 1.00)
Weight predialysis, per kg0.99 (0.99 to 1.00)
Preweight − postweight, per kg1.05 (0.98 to 1.12)
BMI, per kg/m21.00 (0.99 to 1.01)
Treatment time, per min1.00 (1.00 to 1.00)
Smoking (1= yes)1.09 (0.99 to 1.20)
Ethnicity (1= white)0.82 (0.72 to 0.94)
Diabetes1.13 (1.03 to 1.23)
Coronary artery disease1.63 (1.46 to 1.82)
Congestive heart failure1.66 (1.52 to 1.81)
Peripheral vascular disease0.99 (0.90 to 1.09)
Dementia1.26 (0.96 to 1.65)
Chronic bronchopulmonary disease1.16 (1.03 to 1.31)
Paraplegia0.83 (0.46 to 1.50)
Liver disease1.01 (0.88 to 1.16)
Connective tissue disorder1.16 (0.82 to 1.63)
Cerebrovascular disease1.11 (0.98 to 1.25)
Hb, per g/L0.98 (0.98 to 0.99)
Albumin, per g/L0.93 (0.92 to 0.94)
Na, per mmol/L0.97 (0.95 to 0.98)
Phosphate, per mg/dl1.03 (0.99 to 1.07)
LDL, per mg/dl1.00 (1.00 to 1.00)
HDL, per mg/dl1.00 (1.00 to 1.00)
CRP, per mg/L1.04 (1.03 to 1.06)
PCRn, per g/kg per d0.81 (0.73 to 0.89)
Kt/V0.97 (0.96 to 0.98)
Use of AHT medication (1= yes)1.13 (1.03 to 1.23)
  • In this analysis, systolic BP, predialysis weight, and postdialysis weight (and the difference between predialysis weight and postdialysis weight) of the days on which fluid volume (BMC) was measured were averaged and taken as study variables for the multivariate Cox regression. All comorbidities: 1= yes. BMI, body mass index; Hb, hemoglobin; Na, sodium; CRP, C-reactive protein; PCRn, normalized protein catabolic rate; AHT, antihypertensive treatment.