Table 2.

Multivariate Cox regression model of the risk of death associated with FO measured at baseline across systolic BP categories

VariablesHR (95% CI)
BP<130 FO normal1.13 (1.04 to 1.24)
BP<130 FO high1.51 (1.38 to 1.65)
BP=130–160, FO normal1.00 (Reference)
BP=130–160, FO high1.25 (1.16 to 1.36)
BP>160, FO normal1.05 (0.94 to 1.17)
BP>160, FO high1.30 (1.19 to 1.42)
Sex (1= man)0.99 (0.93 to 1.06)
Age, per yr1.04 (1.03 to 1.04)
Height, per cm1.00 (1.00 to 1.01)
Weight predialysis, per kg0.99 (0.99 to 0.99)
Preweight − postweight, per kg1.04 (1.03 to 1.05)
BMI, per kg/m21.00 (1.00 to 1.00)
Treatment time, per min1.00 (1.00 to 1.00)
Smoking (1= yes)1.00 (0.94 to 1.07)
Ethnicity (1= white)0.75 (0.70 to 0.81)
Diabetes1.01 (0.95 to 1.07)
Coronary artery disease1.75 (1.62 to 1.88)
Congestive heart failure1.70 (1.61 to 1.81)
Peripheral vascular disease0.86 (0.80 to 0.92)
Dementia1.28 (1.07 to 1.54)
Chronic bronchopulmonary disease1.03 (0.94 to 1.12)
Paraplegia1.03 (0.69 to 1.52)
Liver disease0.99 (0.90 to 1.10)
Connective tissue disorder1.23 (0.99 to 1.53)
Cerebrovascular disease1.13 (1.05 to 1.23)
Hb, per g/L1.00 (1.00 to 1.00)
Albumin, per g/L0.94 (0.94 to 0.95)
Na, per mmol/L0.99 (0.98 to 0.99)
Phosphate, per mg/dl1.00 (0.99 to 1.02)
LDL, per mg/dl1.00 (1.00 to 1.00)
HDL, per mg/dl0.99 (0.99 to 1.00)
CRP, per mg/L1.03 (1.02 to 1.03)
PCRn, per g/kg per day0.99 (0.97 to 1.00)
Kt/V1.00 (1.00 to 1.00)
Use of AHT medication (1= yes)0.94 (0.89 to 0.99)
  • Patients were classified as overhydrated or nonoverhydrated after dividing the cumulative FO by the days of exposure. Such calculation takes back the cumulative estimate to the original scale (single measurement). All comorbidities: 1= yes. BMI, body mass index; Hb, hemoglobin; Na, sodium; CRP, C-reactive protein; PCRn, normalized protein catabolic rate; AHT, antihypertensive treatment.