Table 1.

Baseline characteristics in incident patients as categorized on the basis of the baseline FO measurement

VariablesOverhydrated (Men: FO≥15%, Women: FO≥13%)Nonoverhydrated (Men: FO<15%, Women: FO<13%)P ValueAll Subjects
Patients, N18,37121,19539,566
Follow-up, d474±351518±362<0.001497±358
Women/men, N (%)7144/11,227 (38.9/61.1)8829/12,366 (41.7/58.3)<0.00115,973/23,593 (40.4/59.6)
Age, yr61.0±15.560.8±15.90.3260.9±15.7
Height, cm165.4±9.8164.5±10.0<0.001164.9±9.9
Weight predialysis, kg70.6±16.474.2±16.7<0.00172.5±16.7
Preweight − postweight, kg1.9±1.31.4±1.6<0.0011.6±1.5
BMI predialysis, kg/m226.1±16.327.9±20.2<0.00127.1±18.5
BP predialysis, mmHg146±26/75±15138±24/73±14<0.001142±25/74±15
Treatment time, min233±34232±380.03232±36
Patients on antihypertensive drugs, %54.851.4<0.00153.0
Patients with catheter, N (%)10,930 (59.5)10,168 (48.0)<0.00121,098 (53.3)
Patient smoking, N (%)3881 (21.1)4305 (20.3)0.058186 (20.7)
Ethnicity: white, N (%)15,103 (82.2)18,253 (86.1)<0.00133,356 (84.3)
Comorbidities
 Diabetes, %31.620.9<0.00125.9
 Coronary artery disease, N (%)1258 (6.8)1183 (5.6)<0.0012441 (6.2)
 Congestive heart failure, N (%)3555 (19.4)3051 (14.4)<0.0016606 (16.7)
 Cerebrovascular disease (stroke), N (%)1987 (10.8)2246 (10.6)0.484233 (10.7)
 Peripheral vascular disease, N (%)2232 (12.1)2096 (9.9)<0.0014328 (10.9)
 Dementia, N (%)157 (0.9)130 (0.6)<0.01287 (0.7)
 Chronic bronchopulmonary disease, N (%)1304 (7.1)1338 (6.3)0.0022642 (6.7)
 Paraplegia, N (%)51 (0.3)56 (0.3)0.80107 (0.3)
 Liver disease, N (%)1393 (7.6)1384 (6.5)<0.0012777 (7.0)
 Connective tissue disorder, N (%)301 (1.6)263 (1.2)<0.001564 (1.4)
Biochemical measurements
 Hb, g/dl9.5±1.710.3±1.7<0.0019.9±1.7
 Albumin, g/dl3.5±0.63.8±0.5<0.0013.7±0.5
 Na, mmol/L137.8±4.6137.7±4.20.65137.8±4.4
 Phosphate, mg/dl4.6±1.74.8±1.7<0.0014.7±1.7
 LDL cholesterol, mg/dl97.8±55.1100.9±155.70.0299.5±120.0
 HDL cholesterol, mg/dl42.8±16.740.8±15.4<0.00141.7±16.1
 CRP, mg/L20.2±38.815.8±31.1<0.00117.8±34.9
 Kt/V1.38±1.941.37±1.930.801.37±1.93
 PCRn, g/kg per d0.9±0.81.0±0.6<0.0011.0±0.7
 FO predialysis, L4.8±2.80.9±1.5<0.0012.7±2.9
  • BMI, body mass index; Hb, hemoglobin; Na, sodium; CRP, C-reactive protein; PCRn, normalized protein catabolic rate.