Table 2.

Risk factors for ESRD in living kidney donors

CharacteristicaHRaP Value
Men (at age 40) 1.88 (95% CI, 1.50 to 2.35)<0.001
black race (at age 40)2.96 (95% CI, 2.25 to 3.89)<0.001
Age per 10 yr: nonblack1.40 (95% CI, 1.23 to 1.59)<0.001
Age per 10 yr: black0.88 (95% CI, 0.72 to 1.09)0.3
BMI per 5 kg/m21.61 (95% CI, 1.29 to 2.00)<0.001
First-degree biologically related to recipient1.70 (95% CI, 1.24 to 2.34)<0.01
  • a Male sex and greater BMI were associated with higher risk of ESRD (both P<0.001). Older age was associated with higher risk of ESRD in nonblack male donors (P<0.001), but the association between age and risk was not statistically significant in black donors (P=0.1). Donors who were closely related to their recipient had higher risk of ESRD (P<0.01).