Table 2.

Response to IIS treatment episodes during the first year after disease onset in 612 patients with SRNS

Treatment Episodes (±Oral Steroid, ±RAS)Complete RemissionPartial RemissionNo RemissionTotal
Oral
 CNI129 (29.8)82 (18.9)222 (51.3)433
 CPH9 (9.2)8 (8.2)81 (82.7)98
 MMF2 (8.3)2 (8.3)20 (83.3)24
 CNI + MMF4 (11.8)10 (29.4)20 (58.8)34
iv Pulse
 Steroid pulse16 (6.8)25 (10.6)195 (82.6)236
iv + Oral
 Steroid pulse + CNI4 (8.2)5 (10.2)40 (81.6)49
 Steroid pulse + other1 (5.9)1 (5.9)15 (88.2)17
 CPH pulse ± other1 (12.5)1 (12.5)6 (75.0)8
 Rituximab ± other2 (28.6)05 (71.4)7
All first-year treatment episodes168 (18.5)134 (14.8)604 (66.7)906
Best response in treated patients150 (24.5)101 (16.5)361 (59.0)612
  • In total, 232 (38%) patients were treated with more than one treatment protocol during the first year after disease onset. Most efficacious treatment was used to classify patients. Data are given as number (percentage). RAS, renin-angiotensin system; CPH, cyclophosphamide.