Table 2.

Results from Cox proportional hazards regression models

Predictors and OutcomesModel 1aP ValueModel 2bP ValueModel 3cP Value
ESRD (dialysis or transplantation)
 Event, n70
 Follow-up time median (IQR)5.19 (1.38–5.88)
 Event rate, 100 person-yr4.17
 Sleep duration, per 1 h lower, n=3971.29 (1.08 to 1.55)<0.011.30 (1.06 to 1.58)0.011.15 (0.91 to 1.46)0.25
 Sleep fragmentation, per 1% higher, n=3971.04 (1.02 to 1.06)<0.0011.05 (1.03 to 1.07)<0.0011.04 (1.01 to 1.07)0.01
 Sleep start time, per 1 h later, n=3971.09 (0.96 to 1.24)0.201.10 (0.94 to 1.27)0.231.13 (0.92 to 1.38)0.25
 PSQI, per one score point higher, n=3540.99 (0.93 to 1.06)0.830.99 (0.92 to 1.06)0.820.98 (0.90 to 1.07)0.68
 ESS, per one score point higher, n=3851.00 (0.95 to 1.05)0.991.02 (0.96 to 1.07)0.511.04 (0.98 to 1.11)0.21
All-cause mortality
 Event, n48
 Follow-up time median (IQR)5.42 (1.52–6.03)
 Event rate, 100 person-yr2.61
 Sleep duration, per 1 h lower, n=3971.15 (0.94 to 1.42)0.171.13 (0.90 to 1.42)0.311.02 (0.79 to 1.31)0.88
 Sleep fragmentation, per 1% higher, n=3971.04 (1.01 to 1.06)0.0041.03 (1.00 to 1.07)0.081.03 (0.99 to 1.06)0.18
 Sleep start time, per 1 h later, n=3970.94 (0.78 to 1.15)0.560.94 (0.75 to 1.18)0.590.95 (0.75 to 1.21)0.68
 PSQI, per one score point higher, n=3541.06 (0.99 to 1.14)0.101.07 (0.98 to 1.17)0.121.05 (0.95 to 1.16)0.34
 ESS, per one score point higher, n=3851.12 (1.05 to 1.19)<0.0011.14 (1.06 to 1.23)<0.0011.11 (1.02 to 1.20)0.01
  • Sample sizes presented correspond to the final model.

  • a Model 1: adjusted for clinical site, age, sex, and education.

  • b Model 2: adjusted for variables in model 1 plus smoking, time-updated systolic BP, diabetes, BMI, cardiovascular disease, and urine sodium (millimoles per liter).

  • c Model 3: adjusted for variables in model 2 plus log UPCR and eGFR.