Table 2.

Incident rate of renal outcomes in overall study cohort and according to quartiles of annual average county PM2.5 concentrations

OutcomeOverall CohortPM2.5 Quartile 1, 5.0–9.1 μg/m3PM2.5 Quartile 2, 9.2–11.0 μg/m3PM2.5 Quartile 3, 11.1–12.6 μg/m3PM2.5 Quartile 4, 12.7–22.1 μg/m3
Incident rate (95% CI) of incident eGFR <60 ml/min per 1.73 m2a7813.22 (7811.62 to 7814.82)6751.90 (6747.88 to 6755.91)7493.88 (7490.48 to 7497.28)7734.59 (7730.88 to 7738.30)8376.30 (8373.60 to 8379.01)
Incident rate (95% CI) of incident CKDb4118.50 (4117.43 to 4119.57)3430.86 (3427.65 to 3434.07)3888.67 (3886.47 to 3890.86)4052.62 (4050.81 to 4054.42)4516.87 (4514.78 to 4518.97)
Incident rate (95% CI) of ≥30% decline in eGFR4740.79 (4739.87 to 4741.71)3876.58 (3874.16 to 3879.00)4504.68 (4503.00 to 4506.35)4684.52 (4682.84 to 4686.20)5191.62 (5190.32 to 5192.92)
Incident rate (95% CI) of ESRD44.36 (44.27 to 44.45)26.71 (26.55 to 26.87)36.91 (36.75 to 37.07)43.53 (43.36 to 43.71)55.60 (55.44 to 55.75)
  • Incidents rates are adjusted for age, race, sex, and T0 eGFR, and standardized to the overall cohort. Incident rate is per every 100,000 person years.

  • a Incident eGFR <60 ml/min per 1.73 m2 was evaluated in a subcohort of people with no prior history of eGFR ≤60 ml/min per 1.73 m2 at time of cohort entry.

  • b Incident CKD was evaluated in a subcohort of people with at least two eGFR measurements separated by at least 90 days who had no prior history eGFR ≤60 ml/min per 1.73 m2 at time of cohort entry.